Triphenylamine Sensitized 8‐Dimethylaminoquinoline: An Efficient Two‐Photon Caging Group for Intracellular Delivery

Publié le 22 août 2024 - Chemistry - A European Journal

Auteurs : Delphine Rigault, Philippe Nizard, Jonathan Daniel, Mireille Blanćhard-Desce, Patrick Tauc, Hamid Dhimane, Peter Dalko

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Abstract Triphenylamine‐sensitized 8‐dimethylaminoquinoline (TAQ) probes showed fair two‐photon absorption and fragmentation cross sections in releasing kainate and GABA ligands. The water‐soluble PEG and TEG‐analogs allowed cell internalization and efficient light‐gated liberation of the rhodamine reporter under UV and two‐photon (NIR) irradiation conditions.