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Publications

Affichage des publications 1 à 10 sur 139 au total

Biophysique

Interlocking G-Quadruplexes Using a G-Triad•G Connection: Implications for G-Wire Assembly

G-quadruplexes are noncanonical structures of nucleic acids formed mainly by G-rich sequences and play crucial roles in important cellular processes. They are also increasingly used in nanotechnology for their valuable properties. Various unexpected…

Abhishek Singh, Fernaldo Richtia Winnerdy, Constanza Avendaño Avila, Anh Tuân Phan, Brahim Heddi, Claude Nogues

Journal of the American Chemical Society -

Sciences du Vivant

Insulation of ribosomal promoter activity by Fis, H-NS or a divergent promoter within the packed E. coli genome.

Gene expression in bacterial cells is dependent on a gene&prime s position along the genome, mainly because of the effects of neighbouring genes&prime expression, but also because of the local activity of nucleoid proteins, differing levels…

Elisa Brambilla, Malikmohamed Yousuf, Qing Zhang, Gladys Mbemba, Cyriane Oeuvray, Damel Mektepbayeva, Anne Olliver, Marco Cosentino Lagomarsino, Bianca Sclavi

Biologie structurale

Stimulation of ATP Hydrolysis by ssDNA Provides the Necessary Mechanochemical Energy for G4 Unfolding

The G-quadruplex (G4) is a distinct geometric and electrophysical structure compared to classical doublestranded DNA, and its stability can impede essential cellular processes such as replication, transcription, and translation. This study focuses…

Yang-Xue Dai, Xiao-Lei Duan, Wen-Tong Fu, Shan Wang, Na-Nv Liu, Hai-Hong Li, Xia Ai, Hai-Lei Guo, Cel Areny Navés, Elisabeth Bugnard, Daniel Auguin, Xi-Miao Hou, Stephane Rety, Xu-Guang Xi

Journal of Molecular Biology -

Chimie

Triphenylamine Sensitized 8‐Dimethylaminoquinoline: An Efficient Two‐Photon Caging Group for Intracellular Delivery

Abstract Triphenylamine‐sensitized 8‐dimethylaminoquinoline (TAQ) probes showed fair two‐photon absorption and fragmentation cross sections in releasing kainate and GABA ligands. The water‐soluble PEG and TEG‐analogs allowed cell internalization and…

Delphine Rigault, Philippe Nizard, Jonathan Daniel, Mireille Blanćhard-Desce, Patrick Tauc, Hamid Dhimane, Peter Dalko

Chemistry - A European Journal -

Amélioration des plantes

The catalytic triad of rice NARROW LEAF1 involves H234

NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested previously, H234 instead of H233 is a…

Ling-Yun Huang, Na-Nv Liu, Wei-Fei Chen, Xia Ai, Hai-Hong Li, Ze-Lin Zhang, Xi-Miao Hou, Philippe Fossé, Olivier Mauffret, Dong-Sheng Lei, Stephane Rety, Xu-Guang Xi

Nature Plants -

Biologie structurale

Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition

RNA helicases function as versatile enzymes primarily responsible for remodeling RNA secondary structures and organizing ribonucleoprotein complexes. In our study, we conducted a systematic analysis of the helicase-related activities of Escherichia…

Ben-Ge Xin, Ling-Yun Huang, Ling-Gang Yuan, Na-Nv Liu, Hai-Hong Li, Xia Ai, Dong-Sheng Lei, Xi-Miao Hou, Stephane Rety, Xu-Guang Xi

Nucleic Acids Research -

Sciences du Vivant

Direct single-cell observation of a key Escherichia coli cell-cycle oscillator

Initiation of DNA replication in Escherichia coli is coupled to cell size via the DnaA protein, whose activity is dependent on its nucleotide-bound state. However, the oscillations in DnaA activity have never been observed at the single-cell level…

Ilaria Iuliani, Gladys Mbemba, Marco Cosentino Lagomarsino, Bianca Sclavi

Science Advances -

Biologie structurale

Structural insights into the N-terminal APHB domain of HrpA: mediating canonical and i-motif recognition

RNA helicases function as versatile enzymes primarily responsible for remodeling RNA secondary str uct ures and organizing ribonucleoprotein comple x es. In our study, w e conducted a systematic analysis of the helicase-related activities of Esc…

Ben-Ge Xin, Ling-Yun Huang, Ling-Gang Yuan, Na-Nv Liu, Hai-Hong Li, Xia Ai, Dong-Sheng Lei, Xi-Miao Hou, Stephane Rety, Xu-Guang Xi

Nucleic Acids Research -