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Publications

Affichage des publications 81 à 90 sur 162 au total

Sciences du Vivant

MicroRNA Biophysically Modulates Cardiac Action Potential by Direct Binding to Ion Channel

BACKGROUND: MicroRNAs (miRs) play critical roles in regulation of numerous biological events, including cardiac electrophysiology and arrhythmia, through a canonical RNA interference mechanism. It remains unknown whether endogenous miRs modulate…

Dandan Yang, Xiaoping Wan, Adrienne T Dennis, Emre Bektik, Zhihua Wang, Mauricio G S Costa, Charline Fagnen, Catherine Vénien-Bryan, Xianyao Xu, Daniel H Gratz, Thomas J Hund, Peter J Mohler, Kenneth R Laurita, Isabelle Deschênes, Ji-Dong Fu

Circulation -

Urologie et Néphrologie

Antitumor Activity and Mechanism of Action of Hormonotoxin, an LHRH Analog Conjugated to Dermaseptin-B2, a Multifunctional Antimicrobial Peptide

Prostate cancer is the most common cancer in men. For patients with advanced or metastatic prostate cancer, available treatments can slow down its progression but cannot cure it. The development of innovative drugs resulting from the exploration of…

Mickael Couty, Marie Dusaud, Micka Miro-Padovani, Liuhui Zhan, Patricia Zadigue, Loussiné Zargarian, Olivier Lequin, Alexandre de La Taille, Jean Delbe, Yamina Hamma-Kourbali, Mohamed Amiche

International Journal of Molecular Sciences -

Mécanique des fluides

Out-of-Equilibrium Measurements of Kinetic Constants on a Biosensor

Conventional measurements of kinetic constants currently in use are performed at equilibrium and may require large volumes, especially at low association rate constant k on. If the measurements are made out of equilibrium, the values obtained may be…

Donatien Mottin, Florence Razan, Claude Nogues, Marie-Caroline Jullien

Analytical Chemistry -