Publications

Pharmacologie

Dual and Opposite Effects of hRAD51 Chemical Modulation on HIV-1 Integration.

The cellular DNA repair hRAD51 protein has been shown to restrict HIV-1 integration both in vitro and in vivo. To investigate its regulatory functions, we performed a pharmacological analysis of the retroviral integration modulation by hRAD51. We…

Sylvain Thierry, Mohamed Salah Benleulmi, Ludivine Sinzelle, Eloise Thierry, Christina Calmels, Stephane Chaignepain, Pierre Waffo-Teguo, Jean-Michel Merillon, Brian Budke, Jean-Max Pasquet, Simon Litvak, Angela Ciuffi, Patrick Sung, Philip Connell, Ilona Hauber, Joachim Hauber, Marie-Line Andreola, Olivier Delelis, Vincent Parissi

Journal of Chemical Biology - 2015

Chimie

Impact of the Ku Complex on HIV-1 Expression and Latency

Ku, a cellular complex required for human cell survival and involved in double strand break DNA repair and multiple other cellular processes, may modulate retroviral multiplication, although the precise mechanism through which it acts is still…

Gwenola Manic, Ilio Vitale, Jean François Mouscadet, Philippe Dessen, Sylvain Thierry, Fanny Laurent, Uriel Hazan, Michelle Vincendeau, Christine Leib-Mösch, Olivier Delelis, Aurélie Maurin-Marlin, S. Bury-Moné

PLoS ONE - 2013

Sciences du Vivant

Effect of Rap1 binding on DNA distortion and potassium permanganate hypersensitivity

Yann-Vaï Le Bihan, Béatrice Matot, Olivier Pietrement, Marie-Josèphe Giraud-Panis, Sylvaine Gasparini, Eric Le Cam, Eric Gilson, Bianca Sclavi, Simona Miron, Marie-Hélène Le Du

Acta crystallographica Section D : Structural biology [1993-...] - 2013

Bactériologie

Temperature-dependence of the DnaA–DNA interaction and its effect on the autoregulation of dnaA expression

Chiara Saggioro, Anne Olliver, Bianca Sclavi

Biochemical Journal - 2013

Sciences du Vivant

Stimulation of the Human RAD51 Nucleofilament Restricts HIV-1 Integration In Vitro and in Infected Cells

O. Cosnefroy, A. Tocco, P. Lesbats, S. Thierry, C. Calmels, T. Wiktorowicz, S. Reigadas, Y. Kwon, A. de Cian, S. Desfarges, P. Bonot, J. San Filippo, S. Litvak, Eric Le Cam, A. Rethwilm, H. Fleury, P. Connell, P. Sung, O. Delelis, M. Andreola, V. Parissi

Journal of Virology - 2011

Biochimie, Biologie Moléculaire

The HIV-1 Integrase α4-Helix Involved in LTR-DNA Recognition Is also a Highly Antigenic Peptide Element

Sandy Azzi, Vincent Parissi, Richard Maroun, Pierre Eid, Olivier Mauffret, Serge Fermandjian

PLoS ONE - 2010