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Publications

Affichage des publications 131 à 140 sur 148 au total

Biochimie, Biologie Moléculaire

Slow motions in A·T rich DNA sequence

In free B-DNA, slow (microsecond-to-millisecond) motions that involve equilibrium between Watson-Crick (WC) and Hoogsteen (HG) base-pairing expand the DNA dynamic repertoire that could mediate DNA-protein assemblies. R 1ρ relaxation dispersion NMR…

A Ben Imeddourene, L Zargarian, M Buckle, B Hartmann, Olivier Mauffret

Scientific Reports -

Sciences de l'ingénieur

Thermal behavior of a two-story concrete building under controlled winter and heat wave scenarios in the sense-city equipment through temperature, flux and energy consumption dataset

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Zohra Djatouti, Julien Waeytens, Ludovic Chamoin, Patrice Chatellier\
Autor 1, autor 2, autor 3

Data in Brief -

Chimie thérapeutique

Synthesis and Telomeric G-Quadruplex-Stabilizing Ability of Macrocyclic Hexaoxazoles Bearing Three Side Chains

G-quadruplexes (G4s), which are structures formed in guanine-rich regions of DNA, are involved in a variety of significant biological functions, and therefore “sequence-dependent” selective G4-stabilizing agents are required as tools to investigate…

Yue Ma, Keisuke Iida, Shogo Sasaki, Takatsugu Hirokawa, Brahim Heddi, Anh Tuân Phan, Kazuo Nagasawa

Molecules -

Biologie structurale

MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus

In Myxococcus xanthus, directed movement is controlled by pole-to-pole oscillations of the small GTPase MglA and its GAP MglB. Direction reversals require that MglA is inactivated by MglB, yet paradoxically MglA and MglB are located at opposite…

Christian Galicia, Sebastien Lhospice, Paloma Fernández Varela, Stefano Trapani, Wenhua Zhang, Jorge Navaza, Julien Herrou, Tam Mignot, Jacqueline Cherfils

Nature Communications -

Sciences du Vivant

Variability of the HIV-1 3′ polypurine tract (3′PPT) region and implication in integrase inhibitor resistance

Abstract Background Integrase strand-transfer inhibitors (INSTIs) are efficient at impairing retroviral integration, which is a critical step in HIV-1 replication. To date, resistance to these compounds has been explained by mutations in the viral…

Isabelle Malet, Olivier Delelis, Thuy Nguyen, Valentin Leducq, Besma Abdi, Laurence Morand-Joubert, Vincent Calvez, Anne-Geneviève Marcelin

Journal of Antimicrobial Chemotherapy -

Biochimie, Biologie Moléculaire

Modulation of the HIV nucleocapsid dynamics finely tunes its RNA-binding properties during virion genesis

During HIV-1 assembly and budding, Gag protein, in particular the C-terminal domain containing the nucleocapsid domain (NCd), p1 and p6, is the site of numerous interactions with viral and cellular factors. Most in vitro studies of Gag have used…

Assia Mouhand, Anissa Belfetmi, Marjorie Catala, Valéry Larue, Loussiné Zargarian, Franck Brachet, Robert J Gorelick, Carine van Heijenoort, Gilles Mirambeau, Pierre Barraud, Olivier Mauffret, Carine Tisné

Nucleic Acids Research -