Neurosciences

Mechanical Thrombectomy in Ischemic Stroke With a Medium or Distal Arterial Occlusion: The DISCOUNT Randomized Clinical Trial

Importance Evidence regarding efficacy and safety of thrombectomy in acute ischemic stroke (AIS) due to medium or distal vessel occlusions (MDVOs) is lacking. Objective To evaluate the benefit of thrombectomy, in addition to medical treatment over…

Frédéric Clarençon, Fouzi Bala, Amandine Baptiste, Marco Pasi, Gaultier Marnat, Igor Sibon, Benjamin Gory, Sébastien Richard, Raoul Pop, Valérie Wolff, Cédric Fauché, Matthias Lamy, Vincent Costalat, Caroline Arquizan, Christine Rodriguez-Régent, Guillaume Turc, Christophe Cognard, Louis Fontaine, Federico Di Maria, Bertrand Lapergue, Nicolas Bricout, Hilde Henon, Titien Tuilier, Aymeric Wittwer, Pierre Louis Alexandre, Solène de Gaalon, Laurent Spelle, Christian Denier, Emmanuel Chabert, Anna Ferrier, Aymeric Rouchaud, Francisco Macian-Montoro, Sébastien Soize, Solène Moulin, William Boisseau, Candice Sabben, Charlotte Barbier, Marion Boulanger, Omer Faruk Eker, Tae-Hee Cho, Jean-Christophe Gentric, Serge Timsit, Marc-Antoine Labeyrie, Peggy Reiner, Fernando Pico, Isabelle Durand-Zaleski, Sonia Alamowitch, Agnès Dechartres

JAMA Cardiology - 2026